As part of our mission to deliver the latest medical breakthroughs, CSSIFM physicians conduct clinical trials that test new treatments for a wide range of patients and cancer types. The following trials are being conducted at CSSIFM and new ones are on the horizon. Please fill out the Clinical Trial Inquiry to get more information.

NANT Triple Negative Breast Cancer (TNBC) Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects with TNBC Who Have Progressed on or After Standard-of-care Therapy
https://clinicaltrials.gov/ct2/show/NCT03387085
Indication: Triple Negative Breast Cancer
NCT03387085 | QUILT-3.067

A Phase 2, Open-Label, Randomized Study of ALT-803, a Fusion Protein Activator of Natural Killer and T-Cells, in Combination With Pembrolizumab vs Pembrolizumab Alone as First-Line Treatment for Patients With Metastatic NSCLC
https://clinicaltrials.gov/ct2/show/NCT03520686
Indications: Non Small Cell Lung Cancer
NCT03520686 | QUILT 2.023

A Phase IIb, Single-Arm, Open-Label Study of ALT-803 in Combination With Pembrolizumab or Nivolumab in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Disease Progression Following an Initial Response to Treatment With PD-1 Checkpoint Inhibitor Therapy
https://clinicaltrials.gov/ct2/show/NCT03228667
Indications: Non-Small Cell Lung Cancer
NCT03228667 | QUILT 3.055

A Phase 2 Study of AMG 337 in Subjects with Advanced or Metastatic Clear Cell Sarcoma that Contains the EWSR1-ATF1 Gene Fusion
https://clinicaltrials.gov/ct2/show/NCT03132155
Indication: Clear Cell Sarcoma
NCT03132155 | QUILT-3.031

A Phase 2 Study of AMG 337 in Subjects with Advanced or Metastatic Solid Tumors that Overexpress MET or Harbor MET EXON 14Skipping (METEX14DEL) Mutations
https://clinicaltrials.gov/ct2/show/NCT03147976
Indication: Solid Tumors
NCT03147976 | Quilt-3.036

An Open-label, Single-arm, Phase 1b/2 Study of NANT-008 in Combination With 5-fluorouracil, Bevacizumab, Leucovorin, and Oxaliplatin in Patients With Metastatic Pancreatic Adenocarcinoma
https://clinicaltrials.gov/ct2/show/NCT03127124
Indications: Pancreatic Adenocarcinoma
NCT03127124 | QUILT 2.022

NANT Neoepitope Yeast Vaccine (Ye-Neo-001): Adjuvant Immunotherapy Using A Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects With Previously Treated Cancers
https://clinicaltrials.gov/ct2/show/NCT03552718
Indications: Solid Cancers
NCT03552718 | QUILT 2.025